Enlist Duo containing the choline salt of 2,4-D and glyphosate was first registered in 2014 for use in genetically engineered corn and soybean in select states, including Nebraska.  After granting the registration, EPA learned that the registrant had made claims of synergy between the ingredients in the herbicide’s formula that had not been shared with EPA at the time of registration. EPA requested and received a court-ordered remand in January 2016 to review synergy data from the registrant.   

On Tuesday (Nov. 1) EPA announced that review of additional data on synergy confirmed EPA’s initial findings of no synergy in the Enlist Duo formulation.

"These data demonstrate that the combination of 2,4-D choline and glyphosate in Enlist Duo does not show any increased toxicity to plants and is therefore not of concern," according to the EPA release.

At this time, EPA is also seeking public comment on a proposed amendment to the registration to include GE cotton and to extend the use for GE corn, soybean and cotton to an additional 19 states.

Enlist Duo is currently registered for use on GE corn and soybean crops in Arkansas, Illinois, Indiana, Iowa, Kansas, Louisiana, Minnesota, Mississippi, Missouri, Nebraska, North Dakota, Oklahoma, Ohio, South Dakota, and Wisconsin. The proposal would extend use on genetically engineered corn, soybean and cotton crops to Alabama, Arizona, Colorado, Delaware, Florida, Georgia, Kentucky, Maryland, Michigan,  North Carolina, New Jersey, New Mexico, New York, Pennsylvania, South Carolina, Tennessee, Texas, Virginia, and West Virginia.

Public comments are being accepted on this "Proposed Registration Decision of Enlist Duo^TM Herbicide" until December 1, 2016 to EPA EPA‑HQ‑OPP‑2016‑0594 at www.regulations.gov. After the comment period, EPA will review the comments and says it expects to release a decision in early 2017.

Read more about the Enlist Duo Registration on the EPA website.